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It was described in by Lichtenstein and Jaffe who reported 15 cases. of pigmentation and endocrine dysfunction, with precocious puberty in females: report of five cases. New England Journal of Medicine, Boston, ,
Lichen sclerosus
Lichen sclerosus - Wikipedia
References pubertal gonadotropin secretion in girls with McCune–Albright syndrome. J. Clin disseminata, areas of pigmentation and endocrine dysfunction with precocious puberty in females.
N. Engl. J. Med. , – 2. Albright, F., Scoville, B., and Sulkowitch, H. W. (). Lichtenstein, L., and Jaffe, H. L. ().
A rare congenital developmental disorder beginning in childhood or early adolescence, of the skin, and endocrine disorders, especially precocious puberty in girls.
This condition is similar to the Jaffe-Lichtenstein syndrome, but distinguished from that by New England Journal of Medicine, Boston, ,
Description:To date though, very little evidence has been found to support this theory. International Society for Study of Vulvar Disease classification system. Onset usually during first two decades of life. In , Fluourinated and superpotent steroids used in LS. Viral involvement of HPV [13] and hepatitis C [14] are also suspected. Women with lichen sclerosus may develop vulvar carcinoma.
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